Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Public comment period · §2

Draft supplier comparison table — submissions

The 14 submissions received, published in full with declared interests and secretariat responses.

Document identifier
CEI-CP-033/2
Series
Public comment period
Version
1.0
Published
10 Jun 2025
Last reviewed
10 Jun 2025
Next review
10 Jun 2026
Identifier
10.71829/cei.cp.33
Certainty
Not rated
Cycle
2025 Q2
Window
28 Apr 2025 – 28 May 2025
Status
Closed
Submissions
14

§2Submissions and responses

14 submissions were received. Each is published in full below with its declared interest, the secretariat response and the disposition. The Institute publishes submissions it did not accept in the same form as those it did.

Dr Rosalind Petrossian, BPharm, PhD University department of pharmacy practice · submitting on pharmacy practice
DRAFT-SUPPLIERS-CO/001 received 29 Apr 2025

A printed copy loses the information that makes it checkable

This is a submission on supplier comparison table, from a respondent who reads these documents on paper.

The respondent states that printing a document produces pages without the identifier, the version or the retrieval date, so that a printed copy cannot be tied back to what it was printed from.

The respondent proposes that these be printed in a fixed position on every page.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseAccepted29 Jun 2025

The secretariat accepts this submission. A printed assessment circulates for longer than the browser tab it came from.

The print stylesheet now carries the identifier, version, publication date and retrieval date on every page, expands link destinations into the text, and prints the full reference list rather than a link to it.

Eamon Sandringham-Adu, MSc (Clinical Pharmacy) Regional hospital pharmacy department · submitting on medicines information
DRAFT-SUPPLIERS-CO/002 received 01 May 2025

A withdrawn document should not simply disappear

The respondent notes that supplier comparison table will govern a great many documents, and submits accordingly.

The respondent states that a reader arriving from an external citation at a withdrawn document needs to know that it existed, that it was withdrawn and why, and that a redirect to an index gives none of that.

The respondent proposes a notice at the original address.

Declared interest. Has received travel support to attend a scientific meeting from a manufacturer of a compound named in the draft.
Secretariat responseAccepted03 Jun 2025

The secretariat accepts this submission. A silent removal makes the citation that led there unresolvable.

A withdrawn document is now replaced at its own address by a notice recording its identifier, its title, the date and ground of withdrawal, and a link to whatever supersedes it, and the withdrawal is recorded in the corrections log.

Dr Frideswide Nordhagen, BPharm, PhD University department of pharmacy practice · submitting on pharmacy practice
DRAFT-SUPPLIERS-CO/003 received 02 May 2025

A printed copy loses the document identifier

The respondent’s comment on supplier comparison table arises from consulting the series for reference rather than writing for it.

A page printed and circulated arrives without the identifier, the version or the date, so a recipient cannot tell whether it is current or find it again.

The respondent proposes that the print stylesheet carry all three in a footer on every page.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted18 Jun 2025

The secretariat accepts this submission.

The print stylesheet now carries the document identifier, the version, the publication date and the address in a footer on every printed page.

Quentin Whitmarsh-Obi, MSc (Clinical Pharmacy) Regional hospital pharmacy department · submitting on medicines information
DRAFT-SUPPLIERS-CO/004 received 03 May 2025

The citation format offered cites the document and not the part

This submission concerns the draft of supplier comparison table. The respondent’s interest is in retrieval: whether a document can be found again, and cited, after it has been superseded.

A reader citing a specific section is given a citation for the whole document, so a citation cannot be checked without reading the whole of it.

The respondent proposes that the citation block offer a part-level citation carrying the section number.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted04 Jun 2025

The secretariat accepts this submission.

The citation block now offers a part-level citation carrying the section number and the part identifier alongside the document-level one.

Dr Quentin Gwynne-Sarpong, MD, MPH Primary-care research network · submitting on public health
DRAFT-SUPPLIERS-CO/005 received 05 May 2025

Indications for which compounds are supplied are absent from the set

This submission addresses supplier comparison table from the standpoint of a reader arriving from a search engine rather than from the front page.

The respondent states that the indication set is drawn from approved and investigated uses, and that several uses for which compounds are widely supplied have no entry, so no document can address them.

The respondent proposes that such uses be added as indications with no anchor outcome and an explicit statement of the evidence position.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted19 Jun 2025

The secretariat accepts this submission. An indication set that omits the uses a reader is most likely to encounter cannot serve that reader.

Uses observed in supply are now included in the indication set, marked as having no approved status and no anchor outcome, and each carries an explicit statement that no trial evidence was identified where that is the case.

Amara Vandergraaf, BA Primary-care research network · submitting on patient and public involvement
DRAFT-SUPPLIERS-CO/006 received 07 May 2025

The front matter delays the reader from reaching the assessment

The respondent has read supplier comparison table in draft and makes one submission.

The respondent states that a reader must pass through identifiers, dates, contributor lists and declarations before reaching any content, and that the most important sentence in the document is the furthest from the top.

The respondent proposes that the front matter be moved to the end.

The respondent supports submission 004 so far as it goes and adds the matter set out here.

Declared interest. Has used a compound in the class under assessment under prescription. Declared at the Institute's request; the Institute regards a lived-experience declaration as an interest and not as a disqualification.
Secretariat responseAccepted in part18 Jun 2025

The secretariat accepts this submission in part. The assessment statement is moved to the top. The front matter is not moved to the end, because it is what allows the assessment to be checked and a document whose provenance is at the bottom will be quoted without it.

Every document now opens with its assessment statement and its certainty rating, with the identifiers, dates and declarations following immediately beneath rather than above, so that the first thing read is the finding and the second is its provenance.

Wilhelmina Oppenheimer-Ade, BA Primary-care research network · submitting on patient and public involvement
DRAFT-SUPPLIERS-CO/007 received 08 May 2025

A multi-part document does not indicate how many parts it has

The respondent has read supplier comparison table and submits on a matter of presentation.

The respondent states that a reader landing on part two of a document from a search result has no indication that parts one and three exist.

The respondent proposes a parts index on every part.

Declared interest. Has used a compound in the class under assessment under prescription. Declared at the Institute's request; the Institute regards a lived-experience declaration as an interest and not as a disqualification.
Secretariat responseNoted, no amendment23 Jun 2025

The secretariat notes this submission. Every part already carries the full parts list in the margin, which the respondent may not have seen at a narrow viewport where the margin is collapsed.

No amendment to structure arises. The parts list is now rendered above the body rather than collapsed at narrow viewports, so that it is visible in the setting where the respondent found it absent.

Yolanda Norrington-Bhatt, MSc (Public Involvement) Primary-care research network · submitting on patient and public involvement
DRAFT-SUPPLIERS-CO/008 received 09 May 2025

A wide table is unusable on a telephone

The draft of supplier comparison table was read from the standpoint of someone who will navigate the series rather than write for it.

Several tables in the series carry more columns than a narrow screen can show, and the reader loses the row heading on scrolling, so a number cannot be attributed to a row.

The respondent proposes that tables be restructured for narrow screens.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted in part16 Jun 2025

The secretariat accepts the diagnosis and adopts a different remedy.

Wide tables scroll within their own container and the first column is held in place, so a value keeps its row heading. Restructuring by screen width was rejected because two readers would then be citing different tables.

Dr Georgiana Mountstephen, MD, FFPH University department of public health · submitting on public health
DRAFT-SUPPLIERS-CO/009 received 10 May 2025

Declared interests should appear on the document rather than on a separate page

The respondent submits on supplier comparison table. A document series is a set of promises about where things will be found, and this submission concerns one of them.

The draft links to a central conflicts register. The respondent argues that a reader assessing whether to rely on a particular document should not have to leave it to find out who assessed it and what they declared.

The respondent proposes that the interests of every named contributor to a document be printed on that document.

Declared interest. Employed by a university department that has received unrestricted research funding from a manufacturer of a compound in the class under assessment. The respondent had no role in that funding.
Secretariat responseNoted, no amendment17 Jun 2025

The secretariat notes this submission and records that the draft already provides for it, which the respondent could reasonably have missed because the provision sits in an appendix.

Every document carries the declared interests of its named contributors in its front matter, and the central register exists so that a reader can see a person across all documents rather than one at a time. No amendment arises; the provision has been moved from the appendix into the body of the methodology document so that it is findable.

Thaddeus Isaksen-Balogun, MSc (Epidemiology) Academic biostatistics group · submitting on biostatistics
DRAFT-SUPPLIERS-CO/010 received 13 May 2025

Point estimates are given without an interval

Having read the draft of supplier comparison table, the respondent puts one point to the secretariat.

Several estimates in the draft appear as single figures. The respondent states that a point estimate without an interval invites a precision the underlying data do not support, and that the effect is worst where the estimate is drawn from a small contributing set.

The respondent proposes that no point estimate appear anywhere in the document set without its interval, including in summary tables and in the abstract.

Declared interest. Employed by a university department that has received unrestricted research funding from a manufacturer of a compound in the class under assessment. The respondent had no role in that funding.
Secretariat responseAccepted in part19 Jun 2025

The secretariat accepts this submission in part. Intervals are added wherever the source reports one. The proposal is declined for figures the source published without an interval, because the Institute will not compute an interval a source did not report.

Every estimate now carries its interval where the source reported one, and where it did not, the estimate is annotated as reported without an interval rather than left to appear as a precise figure.

Professor Bartolomeu Nkosi-Lindegaard, PhD Professor of Regulatory Science · submitting on regulatory science
DRAFT-SUPPLIERS-CO/011 received 20 May 2025

The identifier encodes the document type, which is a property that can change

This submission concerns supplier comparison table and a convention used across the Institute’s output.

An identifier containing a type segment will have to change if a document moves between series, and an identifier that changes is not an identifier.

The respondent proposes that the type segment be dropped or that a commitment be published never to change one.

Declared interest. Is a member of the Institute's external reviewer register but did not review the document under consultation.
Secretariat responseAccepted18 Jun 2025

The secretariat accepts the second limb.

The identifier is retained in its present form and a standing commitment is published that no identifier will be reassigned. A document that moves between series keeps the identifier it was issued with, and the type segment is documented as historical rather than descriptive.

Dr Oisín Rautavaara, PhD (Pharmacoepidemiology) Public-sector clinical trials unit · submitting on biostatistics
DRAFT-SUPPLIERS-CO/012 received 24 May 2025

The same quantity is rounded differently in two parts of one document

This is a submission on supplier comparison table.

A figure appears to one decimal place in the results table and to none in the summary, and in one case the rounding changes which of two values is larger.

The respondent proposes a single rounding convention applied at the point the quantity is computed rather than at each point it is displayed.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseAccepted01 Jul 2025

The secretariat accepts this submission.

Quantities are now rounded once, at computation, and displayed identically wherever they appear. The convention is stated in the series description.

Dr Anselm Thorsby-Nakamura, PhD (Chemistry), CChem Independent analytical consultancy · submitting on analytical chemistry
DRAFT-SUPPLIERS-CO/013 received 26 May 2025

A field the Institute could not verify should be shown rather than omitted

The respondent read supplier comparison table in draft and has confined this submission to a single provision.

The respondent states that omitting an unverifiable field leaves a reader unable to distinguish between a fact that does not exist, a fact the Institute did not seek and a fact it sought and could not confirm.

The respondent proposes that unverified fields be displayed with their status.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseAccepted23 Jun 2025

The secretariat accepts this submission. Three different situations were being rendered identically as blank space.

Every field now carries one of four states, being verified, claimed and unverified, sought and not established, or not applicable, and the state is displayed rather than inferred from an empty cell.

Dr Hyacinth Drakeford-Amadi, BPharm, PhD Community pharmacy practice, doctoral candidate · submitting on pharmacy practice
DRAFT-SUPPLIERS-CO/014 received 26 May 2025

The default ordering of a comparison table carries an implication

The respondent submits on supplier comparison table. The point would apply equally to any document in the series.

The respondent states that whatever column a table is sorted on by default will be read as the column that matters, and that the draft sorts on a score.

The respondent proposes an alphabetical default.

Submission 013 raises an adjacent matter. The respondent regards the two as separable and addresses only this one.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted01 Jul 2025

The secretariat accepts this submission. A default is a claim whether or not it is intended as one.

The default ordering is now alphabetical, a standing statement above every comparison table records that the ordering is not a ranking, and the sort state is reset on reload so that a shared link does not carry an ordering the sender chose.

References cited on this page

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. International Organization for Standardization. ISO/IEC 17025:2017 General Requirements for the Competence of Testing and Calibration Laboratories. ISO/IEC Standard 2017;3rd edition. identifier not held by the Institute

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.