Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Public comment period · §3

Draft certainty index — disposition

The disposition of every submission and the amendments that resulted.

Document identifier
CEI-CP-038/3
Series
Public comment period
Version
1.0
Published
10 Jul 2026
Last reviewed
10 Jul 2026
Next review
10 Jul 2027
Identifier
10.71829/cei.cp.38
Certainty
Not rated
Cycle
2026 Q3
Window
10 Jul 2026 – 07 Aug 2026
Status
Open
Submissions
15

§3Disposition and amendments

§3.1Disposition table

Table 1. Every submission with its disposition. Each row links to the submission in full.

ReferenceRespondentPoint raisedDisposition
DRAFT-CERTAINTY-IN/001Eamon Sandringham-AduReferences should carry a persistent identifier for every cited sourceAccepted in part
DRAFT-CERTAINTY-IN/002Quentin Whitmarsh-ObiThe same quantity is presented differently in two seriesAccepted
DRAFT-CERTAINTY-IN/003Dr Zdenka Nyquist-ObioraThe anchor outcome for an indication is not the outcome a decision turns onAccepted in part
DRAFT-CERTAINTY-IN/004Dr Marisol Dunmore-EkpoA document is split across parts at a point that separates a claim from its supportAccepted in part
DRAFT-CERTAINTY-IN/005Dr Emiliana OllerenshawIndications for which compounds are supplied are absent from the setAccepted
DRAFT-CERTAINTY-IN/006Anselm MountstephenAn identifier that encodes the document type will have to change when the type doesAccepted
DRAFT-CERTAINTY-IN/007Professor Bartolomeu Nkosi-LindegaardThe identifier encodes the document type, which is a property that can changeAccepted
DRAFT-CERTAINTY-IN/008Dr Jozef Brandvold-AchterbergAbsence of evidence is presented in a form a reader will take as negative evidenceAccepted
DRAFT-CERTAINTY-IN/009Ivo MountstephenA withdrawn document should not simply disappearAccepted
DRAFT-CERTAINTY-IN/010Yolanda Norrington-BhattThe front matter delays the reader from reaching the assessmentAccepted in part
DRAFT-CERTAINTY-IN/011Stellan Cholmondeley-AdeA long index is paginated in a way that makes an item hard to find againNoted, no amendment
DRAFT-CERTAINTY-IN/012Dr Vittoria QuintanilhaA section with nothing in it is emitted with a heading and a sentence saying soAccepted
DRAFT-CERTAINTY-IN/013Dr Yusuf Whitmarsh-ObiA document does not show what draws on itAccepted
DRAFT-CERTAINTY-IN/014Dr Vasilisa ImmelmannThe series scope is drawn widely enough to absorb documents that belong elsewhereAccepted in part
DRAFT-CERTAINTY-IN/015Dr Oisín RautavaaraPoint estimates are given without an intervalAccepted in part
15 submissions in total.

§3.2Summary by disposition

Table 2. Counts by disposition, with the meaning of each.

DispositionCountMeaning
Accepted8The submission is accepted and the draft is amended as proposed. The amendment is recorded in the amendment log of the document it changed and is traceable to the numbered submission.
Accepted in part6Part of the submission is accepted and part is not. The secretariat response states which part is which and on what ground the remainder was declined.
Noted, no amendment1The submission raises a point the Institute accepts but that does not require a change to the draft, most often because the draft already states it elsewhere. The location is given in the response.
Not accepted0The submission is not accepted. The secretariat response gives the reason. A submission that is not accepted remains published in full; the Institute does not remove a submission because it disagrees with it.

§3.3Resulting amendments

  1. References should carry a persistent identifier for every cited source — arising from DRAFT-CERTAINTY-IN/001. Every reference without a persistent identifier now carries an explicit statement that the identifier is not held by the Institute, so that its absence is a recorded fact rather than an apparent oversight.
  2. The same quantity is presented differently in two series — arising from DRAFT-CERTAINTY-IN/002. Certainty ratings are now presented identically across every series, using the same badge, the same wording and the same accompanying formulation, and the presentation is specified in the series structure document rather than left to each series.
  3. The anchor outcome for an indication is not the outcome a decision turns on — arising from DRAFT-CERTAINTY-IN/003. One anchor outcome is changed to the outcome proposed, and the second is retained with the alternative recorded as the preferred anchor and listed as an evidence gap, so that the reason for the compromise is on the record.
  4. A document is split across parts at a point that separates a claim from its support — arising from DRAFT-CERTAINTY-IN/004. Every part now carries the certainty rating in its own metadata header and repeats it beside any estimate it reproduces, so that no page presents an estimate without its rating.
  5. Indications for which compounds are supplied are absent from the set — arising from DRAFT-CERTAINTY-IN/005. Uses observed in supply are now included in the indication set, marked as having no approved status and no anchor outcome, and each carries an explicit statement that no trial evidence was identified where that is the case.
  6. An identifier that encodes the document type will have to change when the type does — arising from DRAFT-CERTAINTY-IN/006. The identifier is now opaque and permanent from first publication, the series and type are recorded as fields that may change, and a reclassified document keeps the identifier it was issued with.
  7. The identifier encodes the document type, which is a property that can change — arising from DRAFT-CERTAINTY-IN/007. The identifier is retained in its present form and a standing commitment is published that no identifier will be reassigned. A document that moves between series keeps the identifier it was issued with, and the type segment is documented as historical rather…
  8. Absence of evidence is presented in a form a reader will take as negative evidence — arising from DRAFT-CERTAINTY-IN/008. A standing formulation has been adopted and is applied wherever an evidence gap is recorded, distinguishing an outcome assessed and not demonstrated from an outcome not assessed. The formulation is identical at every occurrence so that it can be recognised at…
  9. A withdrawn document should not simply disappear — arising from DRAFT-CERTAINTY-IN/009. A withdrawn document is now replaced at its own address by a notice recording its identifier, its title, the date and ground of withdrawal, and a link to whatever supersedes it, and the withdrawal is recorded in the corrections log.
  10. The front matter delays the reader from reaching the assessment — arising from DRAFT-CERTAINTY-IN/010. Every document now opens with its assessment statement and its certainty rating, with the identifiers, dates and declarations following immediately beneath rather than above, so that the first thing read is the finding and the second is its provenance.
  11. A section with nothing in it is emitted with a heading and a sentence saying so — arising from DRAFT-CERTAINTY-IN/012. A section with no content is now folded into its parent as a single recorded line. The fact of the absence is preserved, because an absent section and an absent statement are different, and the heading is not.
  12. A document does not show what draws on it — arising from DRAFT-CERTAINTY-IN/013. Every trial abstract and every bibliography entry now carries a list of the documents that draw on it, generated from the citations themselves so that it cannot fall out of step.
  13. The series scope is drawn widely enough to absorb documents that belong elsewhere — arising from DRAFT-CERTAINTY-IN/014. The series scope now carries an explicit exclusion list naming the document classes that do not belong to it and stating where each belongs instead, so that a placement decision is checkable rather than editorial.
  14. Point estimates are given without an interval — arising from DRAFT-CERTAINTY-IN/015. Every estimate now carries its interval where the source reported one, and where it did not, the estimate is annotated as reported without an interval rather than left to appear as a precise figure.

References cited on this page

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. International Organization for Standardization. ISO/IEC 17025:2017 General Requirements for the Competence of Testing and Calibration Laboratories. ISO/IEC Standard 2017;3rd edition. identifier not held by the Institute

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

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